Date: 11/18/2025

by: Houriah Y. Nukaly, MD, MSc(c)1; Renad F. Althobaiti, MD2; Waseem K. AlHawsawi, MD et al

This observation describes 2 siblings with LI treated with acitretin and dupilumab, highlighting the potential benefits of combination therapy in managing refractory cases and contributing to the growing literature on biologic agents in congenital ichthyosis. Read more here https://jamanetwork.com/journals/jamadermatology/fullarticle/2840408?guestAccessKey=1bc9cbd9-497a-4db0-87d3-9abaca33cc9a&linkId=871818370