Date: 12/03/2024

A new study on Autosomal Dominant Lamellar Ichthyosis (ADLI), a skin condition, has revealed some exciting findings. The research, led by Komlosi et al. (2024), looked at a large family in Germany affected by this condition. They discovered a new gene location (called a "locus") linked to the disease. They also found a specific mutation in the NKPD1 gene, which causes the skin condition and is passed down through the family. This discovery helps us better understand how skin works and highlights the important role of the NKPD1 gene in skin development. The study confirms that conditions like ichthyosis can offer important clues about how our skin functions at a deeper biological level. Read the Journal of Investigative Dermatology article here: https://www.jidonline.org/article/S0022-202X(24)00446-9/fulltext