Date: 12/07/2016

On September 25, 2016, the FIRST Board of Directors approved funding of Dr. Christopher Bunick for his work in determining the structural mechanisms of ichthyosis-causing mutations by x-ray crystallographic analysis of keratins 1 and 10. The FIRST research grant will provide funding in the amount of $50,000 for a period of one year, beginning October 1, 2016.

Dr. Christopher Bunick is a unique physician-scientist among dermatologists because of his application of x-ray crystallography to the field of dermatology research, bringing an expansive view to the notion of what can scientifically be achieved to help patients. “X-ray crystallography technology enables determination of a 3-D image of what a protein looks like in living cells, therefore I am able to see the structures of the proteins that constitute the human skin barrier. This technology is going to greatly improve our understanding of the science behind skin function,” he explained. When asked about his futuristic vision, Bunick stated, “What I imagine is creating a niche of dermatology research, 'molecular or structural dermatology' so to speak, and one by one, determine 3-D structures of proteins highly relevant to normal and diseased skin. I am excited to tackle many disorders in the field of dermatology from this structural perspective, and my hope would be translation of this work into new classes of therapeutics to help patients with skin disorders.”

Please join the FIRST community in congratulating Dr. Bunick and wishing him all the best as he continues his endeavors into the field of ichthyosis research. Stay tuned for updates on Dr. Bunick’s progress at firstskinfoundation.org.

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