Other names: common ichthyosis, ichthyosis simplex
Inheritance: autosomal semi-dominant
Incidence: 1:250 - 1:5,000
skin: fine, polygonal, flat whitish scales that may be darker on distal extremities; face and flexural areas usually spared; accentuated markings on palms and soles; often scaling around hair follicles on extremities
Associated findings: nasal allergies, asthma or eczema in >50%
Age at first appearance: early childhood; not usually present at birth
Long-term course: lifelong; marked seasonal variation; distinctly worse in dry climates
Diagnostic tests: skin biopsy can be highly suggestive, but not diagnostic
Abnormal gene: profilaggrin (FLG)
Clinicians seeking to confirm a diagnosis should visit FIRST's TeleIchthyosis site to submit a case to experts in ichthyosis.
To learn more about ichthyosis vulgaris, follow this link.
Learn more about FIRST's Regional Support Network - connecting affected individuals and families with each other. Or call the FIRST office at 800.545.3286.
This information is provided as a service to patients and parents of patients who have ichthyosis. It is not intended to supplement appropriate medical care, but instead to complement that care with guidance in practical issues facing patients and parents. Neither FIRST, its Board of Directors, Medical & Scientific Advisory Board, Board of Medical Editors nor Foundation staff and officials endorse any treatments or products reported here. All issues pertaining to the care of patients with ichthyosis should be discussed with a dermatologist experienced in the treatment of their skin disorder.